abstract：:Many studies suggest that catalase C-262T gene polymorphism is associated with cancer risk, but with inconsistent results. This study aimed to summarize the overall association between catalase C-262T polymorphism and cancer risk. Literature search was performed in PubMed, Embase, and other databases, studies regardin...

journal_title：Medicine

authors： Shen Y,Li D,Tian P,Shen K,Zhu J,Feng M,Wan C,Yang T,Chen L,Wen F

更新日期：2015-04-01 00:00:00

abstract：:Papillary renal cell carcinoma (pRCC) is the second most prevalent subtype of kidney cancers. In the current study, we analyzed the global microRNA (miRNA) expression profiles in pRCC, with the aim to evaluate the relationship of miRNA expression with the progression and prognosis of pRCC.A total of 163 treatment-naïv...

journal_title：Medicine

authors： Ge YZ,Xu LW,Xu Z,Wu R,Xin H,Zhu M,Lu TZ,Geng LG,Liu H,Zhou CC,Yu P,Zhao YC,Hu ZK,Zhao Y,Zhou LH,Wu JP,Li WC,Zhu JG,Jia RP

更新日期：2015-04-01 00:00:00

abstract：:Few studies have yet investigated the possible association between high-density lipoprotein cholesterol (HDL-C) and kidney function in elderly patients with primary hypertension. Accordingly, the aim of the present study was to evaluate the relationship between HDL-C and kidney function in elderly hypertension. A tota...

journal_title：Medicine

authors： Zhang YP,Lu MG,Duan DD,Liu YL,Liu M,Li Y,Kuang ZM,Lu Y,Liu X,Li XH,Yuan H

更新日期：2015-04-01 00:00:00

abstract：:Qualitative and quantitative analyses of circulating cell-free DNA (cfDNA) are potential methods for the detection of hepatocellular carcinoma (HCC). Many studies have evaluated these approaches, but the results have been variable. This meta-analysis is the first to synthesize these published results and evaluate the ...

journal_title：Medicine

authors： Liao W,Mao Y,Ge P,Yang H,Xu H,Lu X,Sang X,Zhong S

更新日期：2015-04-01 00:00:00

abstract：:Mucinous adenocarcinoma (MAC) is a histological subtype of colorectal cancer. The oncologic behavior of MAC differs from nonmucinous adenocarcinoma (non-MAC). Our aim in this study was to characterize patients with colorectal MAC through evaluation of a large, institutional-based cohort with long-term follow-up. A tot...

journal_title：Medicine

authors： Park JS,Huh JW,Park YA,Cho YB,Yun SH,Kim HC,Lee WY,Chun HK

更新日期：2015-04-01 00:00:00

abstract：:We present 2 rare cases of patients with uncontrolled hemorrhagic shock induced by traumatic ascending aortic pseudoaneurysm rupture into the esophagus. Two men were presented to the hospital after traffic accidents. Their chest radiograph showed no obvious signs of aortic damage or aortic pseudoaneurysms but only a s...

journal_title：Medicine

authors： He S,Chen X,Zhou X,Hu Q,Ananda S,Zhu S

更新日期：2015-04-01 00:00:00

abstract：:Lateral talar process fragment excision may be followed by hindfoot instability and altered biomechanics. There is controversy regarding the ideal fragment size for internal fixation versus excision and a concern that excision of a large fragment may lead to significant instability. The aim of this study was to assess...

journal_title：Medicine

authors： Sands A,White C,Blankstein M,Zderic I,Wahl D,Ernst M,Windolf M,Hagen JE,Richards RG,Stoffel K,Gueorguiev B

更新日期：2015-03-01 00:00:00

abstract：:Patients with "difficult-to-treat" advanced testicular cancer can require multiple therapies. We retrospectively assessed our patients with advanced germ cell tumors (GCTs) and characterized the clinical efficacy, outcomes, and factors affecting overall survival (OS).Two hundred fifty-three patients with advanced GCTs...

journal_title：Medicine

authors： Nakamura T,Ueda T,Oishi M,Nakanishi H,Shiraishi T,Fujihara A,Naito Y,Kamoi K,Naya Y,Hongo F,Okihara K,Miki T

更新日期：2015-03-01 00:00:00

abstract：:Nocturnal variations in blood pressure (BP) were associated with carotid intima-media thickness. However, the precise relationship between circadian variations of BP and carotid plaques remains unknown. Therefore, the prognostic value of reverse-dipper pattern of BP for carotid plaque was investigated. In this cross-s...

journal_title：Medicine

authors： Yan B,Peng L,Han D,Sun L,Dong Q,Yang P,Zheng F,Ong H,Zeng L,Wang G

更新日期：2015-03-01 00:00:00

abstract：:A minimum of 15 lymph nodes (LNs) has been recommended as an adequate number for radical gastrectomy for gastric cancer (GC). This study aimed to investigate whether the harvesting of at least 25 LNs was a better criterion for stage N2-3 GC based on the 10-year experience of a high-volume hospital. A total of 1363 pat...

journal_title：Medicine

authors： Chen HN,Chen XZ,Zhang WH,Chen XL,Yang K,Liu JP,Zhang B,Chen ZX,Chen JP,Zhou ZG,Hu JK

更新日期：2015-03-01 00:00:00

abstract：:Clinical practice guidelines (CPGs) play an important role in health care. The guideline development process should be precise and rigorous to ensure that the results are reproducible and not vague. To determine the quality of guidelines, the Appraisal of Guidelines and Research and Evaluation (AGREE) instrument was d...

journal_title：Medicine

authors： He Z,Tian H,Song A,Jin L,Zhou X,Liu X,Guo W,Zhang Z

更新日期：2015-03-01 00:00:00

abstract：:This article compares the clinical characteristics and prognosis of young patients in different age groups with liver cancer (LC). In this retrospective study, we searched the Surveillance, Epidemiology, and End Results population-based database and identified 2641 patients who had been diagnosed with LC between 1988 ...

journal_title：Medicine

authors： Zhang W,Jiang R,Hou J,Sun B

更新日期：2015-03-01 00:00:00

abstract：:[In the article "The High Prevalence of Hypovitaminosis D in China: A Multicenter Vitamin D Status Survey", which appeared in Volume 94, Issue 8 of Medicine, several corrections were required regarding various manufacturer locations. The article has since been corrected online.]. ...

journal_title：Medicine

authors：

更新日期：2015-03-01 00:00:00

abstract：:Acute care of stroke victims largely relies on the rapid identification and timely clinical and radiological assessment. We evaluated the effect of the number of patient companions on the efficiency of the diagnostic process in the emergency department (ED).Consecutive stroke patients admitted to the ED between August...

journal_title：Medicine

authors： Ashkenazi L,Toledano R,Novack V,EIluz E,Abu-Salamae I,Ifergane G

更新日期：2015-03-01 00:00:00

abstract：:Immunotherapy with Bacillus Calmette-Guérin (BCG) is the most efficacious treatment for high-risk bladder cancer (BC) (Ta/T1 or carcinoma in situ) to reduce the risk of recurrence. Our aim was to evaluate whether hypertension and diabetes influence the outcome of patients with noninvasive BC treated with BCG instillat...

journal_title：Medicine

authors： Dal Moro F,Bovo A,Crestani A,Vettor R,Gardiman MP,Zattoni F

更新日期：2015-03-01 00:00:00

abstract：:Meta-analyses have found conflicting results with respect to the use of progesterone or progesterone plus estrogen as luteal phase support for in vitro fertilization (IVF) protocols involving gonadotropins and/or gonadotropin-releasing hormone analogs. The aim of the present study was to perform an updated meta-analys...

journal_title：Medicine

authors： Zhang XM,Lv F,Wang P,Huang XM,Liu KF,Pan Y,Dong NJ,Ji YR,She H,Hu R

更新日期：2015-02-01 00:00:00

abstract：:Determination of Fuhrman grade (FG) on biopsies of renal masses is relatively inaccurate, being prone to underestimating the true grade as ascertained from surgical specimens. This study evaluated whether anatomical features of tumors could predict tumor upgrading between core biopsies and surgical specimens. We prosp...

journal_title：Medicine

authors： Zhang GM,Zhu Y,Gan HL,Wang HK,Shi GH,Zhang HL,Dai B,Wang CF,Ye DW

更新日期：2015-02-01 00:00:00

abstract：:Hepatocyte nuclear factor 1 beta (HNF1B) plays an important role in embryonic development, namely in the kidney, pancreas, liver, genital tract, and gut. Heterozygous germline mutations of HNF1B are associated with the renal cysts and diabetes syndrome (RCAD). Affected individuals may present a variety of renal develo...

journal_title：Medicine

authors： Alvelos MI,Rodrigues M,Lobo L,Medeira A,Sousa AB,Simão C,Lemos MC

更新日期：2015-02-01 00:00:00

abstract：:The purpose of study was to analyze the participants' opinions concerning the effectiveness of 6 denture adhesives (DA). The study group included 60 participants. Criteria for selecting the patients were as follows: reduced retention and stabilization of maxillary complete dentures and xerostomia. These features were ...

journal_title：Medicine

authors： Bogucki ZA,Napadlek P,Dabrowa T

更新日期：2015-02-01 00:00:00

abstract：:East Asian patients with diabetes have a higher risk for renal complications and strokes than Europeans. We aimed to evaluate the effect of methylenetetrahydrofolate reductase (MTHFR) gene 677 C → T polymorphism, which was associated with a higher stroke risk and was common in the Chinese population, as well as homocy...

journal_title：Medicine

authors： Qin X,Li Y,Yuan H,Xie D,Tang G,Wang B,Wang X,Xu X,Xu X,Hou F

更新日期：2015-02-01 00:00:00

abstract：:Bisphosphonates have been commonly used for the treatment of osteoporosis. However, there have been recent case reports of atypical fractures citing their long-term use, which inhibits the turnover of bone components. A 64-year-old woman visited the outpatient clinic with pain in her right thigh and ambulation difficu...

journal_title：Medicine

authors： Kim HS,Jung HY,Kim MO,Joa KL,Kim YJ,Kwon SY,Kim CH

更新日期：2015-02-01 00:00:00

abstract：:Some of HER-2 positive breast cancer patients failed to trastuzumab treatment. Recent reports have indicated the correlation between plasma coagulation parameters and clinical characteristics in breast cancer. The aim of this study was to analyze the role of coagulation parameters in trastuzumab treated patients. Coag...

journal_title：Medicine

authors： Liu YL,Lu Q,Liang JW,Xia Y,Zhang W,Hu BQ,Shang FF,Ji YR,Wang J,Wang Q,Liang B

更新日期：2015-02-01 00:00:00

abstract：:Pancreatic cancer is known for its typically late presentation and poor survival rates, with overall 5-year survival of less than 5%. The role of chemotherapy alone or with radiotherapy in the management of locally advanced tumors continues to be an area of debate.We report a case of locally advanced, pancreatic adeno...

journal_title：Medicine

authors： Elias A,Chatzizacharias NA,Xanthis A,Corrie P,Davies S,Brais RJ,Jamieson NV,Praseedom RK,Huguet E,Harper SJF,Jah A

更新日期：2015-02-01 00:00:00

abstract：:To investigate the diurnal variations of the ocular blood flow in healthy eyes using laser speckle flowgraphy (LSFG), and to determine the relationship of the diurnal variations between the ocular blood flow and other ocular parameters.This prospective cross-sectional study was conducted at Nagoya University Hospital....

journal_title：Medicine

authors： Iwase T,Yamamoto K,Ra E,Murotani K,Matsui S,Terasaki H

更新日期：2015-02-01 00:00:00

abstract：:The objective of this study was to investigate the contribution of handgrip strength in predicting the functional outcome after hip fracture in women.We prospectively investigated white women (N = 193 of 207) who were consecutively admitted to a rehabilitation hospital after a hip fracture. We measured handgrip streng...

journal_title：Medicine

authors： Di Monaco M,Castiglioni C,De Toma E,Gardin L,Giordano S,Tappero R

更新日期：2015-02-01 00:00:00

abstract：:Strength training has, in recent years, been shown to be beneficial for people with Parkinson disease and multiple sclerosis. Consensus regarding its utility for these disorders nevertheless remains contentious among healthcare professionals. Greater clarity is required, especially in regards to the type and magnitude...

journal_title：Medicine

authors： Cruickshank TM,Reyes AR,Ziman MR

更新日期：2015-01-01 00:00:00

abstract：:The association between tuberculosis (TB) and lung cancer is well known. However, carcinogenesis of TB and its connection with epidermal growth factor receptor (EGFR) mutation remains unclear. This study aimed to determine this connection to see if TB can affect the outcome of patients with lung cancer. This is a retr...

journal_title：Medicine

authors： Chang CH,Lee CH,Ho CC,Wang JY,Yu CJ

更新日期：2015-01-01 00:00:00

abstract：:Olfactory outcomes as well as oronasal postoperative complications of transsphenoidal pituitary surgery have not been well studied. The objective of this study was to investigate nasal symptoms including olfactory function as well as quality of life following transsphenoidal pituitary surgery. The study is designed as...

journal_title：Medicine

authors： Wang S,Chen Y,Li J,Wei L,Wang R

更新日期：2015-01-01 00:00:00

abstract：:Splanchnic vein thrombosis (SVT) refers to Budd-Chiari syndrome (BCS) and portal vein system thrombosis (PVST). Current practice guidelines have recommended the routine screening for antiphospholipid antibodies (APAs) in patients with SVT. A systematic review and meta-analysis of observational studies was performed to...

journal_title：Medicine

authors： Qi X,De Stefano V,Su C,Bai M,Guo X,Fan D

更新日期：2015-01-01 00:00:00

abstract：:Bisphenol A (BPA), a carbon-based synthetic compound, exhibits hormone-like properties and is present ubiquitously in the environment and in human tissues due to its widespread use and biological accumulation. BPA can mimic estrogen to interact with estrogen receptors α and β, leading to changes in cell proliferation,...

journal_title：Medicine

authors： Gao H,Yang BJ,Li N,Feng LM,Shi XY,Zhao WH,Liu SJ

更新日期：2015-01-01 00:00:00

abstract：:Using nasopharyngeal carriage as a marker of vaccine impact, pneumococcal colonization and its relation to invasive disease were examined in children, their parents, and older adults in the United Kingdom following introduction of 7-valent pneumococcal conjugate vaccine (PCV7) and prior to 13-valent pneumococcal conju...

journal_title：Medicine

authors： Hamaluba M,Kandasamy R,Ndimah S,Morton R,Caccamo M,Robinson H,Kelly S,Field A,Norman L,Plested E,Thompson BAV,Zafar A,Kerridge SA,Lazarus R,John T,Holmes J,Fenlon SN,Gould KA,Waight P,Hinds J,Crook D,Snape MD,

更新日期：2015-01-01 00:00:00

abstract：:End-stage renal disease (ESRD) patients exhibit an increased incidence of peptic ulcer disease. Helicobacter pylori plays a central role in the development of peptic ulcers. The effect of early H pylori eradication on the recurrence of complicated peptic ulcer disease in ESRD patients remains unclear. The aim of the p...

journal_title：Medicine

authors： Chang SS,Hu HY

更新日期：2015-01-01 00:00:00

abstract：:Acute motor axonal neuropathy (AMAN) is a variant of Guillain-Barre syndrome. It has been reported to have no sensory symptoms and is diagnosed by typical electrophysiological findings of low-amplitude or unobtainable compound muscle action potentials with normal sensory nerve action potentials. However, the authors e...

journal_title：Medicine

authors： Lee KS,Han SH

更新日期：2015-01-01 00:00:00

abstract：:Augmentation of implants with polymethylmethacrylate (PMMA) bone cement in osteoporotic fractures is a promising approach to increase implant purchase. Side effects of PMMA for the metaphyseal bone, particularly for the adjacent subchondral bone plate and joint cartilage, have not yet been studied. The following exper...

journal_title：Medicine

authors： Goetzen M,Hofmann-Fliri L,Arens D,Zeiter S,Stadelmann V,Nehrbass D,Richards RG,Blauth M

更新日期：2015-01-01 00:00:00

abstract：:Few studies have analyzed the training of endoscopists in the diagnosis of early gastric cancer (EGC). This study assessed whether specific training of endoscopists improves the detection rate of EGC. The rates of detection of EGC by endoscopists at the Digestive Endoscopy Center of the Affiliated Nanfang Hospital of ...

journal_title：Medicine

authors： Zhang Q,Chen ZY,Chen CD,Liu T,Tang XW,Ren YT,Huang SL,Cui XB,An SL,Xiao B,Bai Y,Liu SD,Jiang B,Zhi FC,Gong W

更新日期：2015-01-01 00:00:00

abstract：:In normal-tension glaucoma (NTG), optic nerve damage occurs despite a normal intraocular pressure. Studies implicating systemic blood pressure or, more recently, arterial stiffness in the pathophysiology of NTG have produced conflicting results. Our aim was to investigate whether NTG is associated with alterations in ...

journal_title：Medicine

authors： Bossuyt J,Vandekerckhove G,De Backer TLM,Van de Velde S,Azermai M,Stevens AM,Kestelyn P,Raemdonck T,Segers P,Vanmolkot F,Van Bortel LM

更新日期：2015-01-01 00:00:00

abstract：:[In the article "Uncompromised Treatment Efficacy in Elderly Patients With Hepatocellular Carcinoma: A Propensity Score Analysis", which appeared in Volume 93, Issue 28 of Medicine, one of the authors' affiliations, National Yang-Ming University School of Medicine, Taipei, Taiwan, was omitted. The article has since be...

journal_title：Medicine

authors：

更新日期：2015-01-01 00:00:00

abstract：:[An uncorrected version of "Comparative Effectiveness of Different Oral Antibiotics Regimens for Treatment of Urinary Tract Infection in Outpatients: An Analysis of National Representative Claims Database" was originally posted in Volume 93, Issue 28 of Medicine. The article has since been corrected and reposted in th...

journal_title：Medicine

authors：

更新日期：2015-01-01 00:00:00

abstract：:This retrospective study compared efficacy and safety of fludarabine combined with intermediate-dose cytarabine (FA regimen) versus high-dose cytarabine (HiDAC regimen) as consolidation therapy in acute myeloid leukemia (AML) patients who achieved complete remission. Disease-free survival (DFS) and overall survival (O...

journal_title：Medicine

authors： Zhang W,Ding Y,Wu H,Chen Y,Lu H,Chen C,Fu J,Wang W,Liang A,Zou S

更新日期：2014-12-01 00:00:00

abstract：:The remarkable success of trastuzumab and other newly developed anti-HER2 (human epidermal growth factor receptor 2) therapies in breast, gastric, or gastroesophageal junction cancer patients has supported us to investigate the HER2 status and its possible therapeutic implication in mucinous epithelial ovarian cancer ...

journal_title：Medicine

authors： Chen CK,Lee MY,Lin WL,Wang YT,Han CP,Yu CP,Chao WR

更新日期：2014-12-01 00:00:00